Loki is the man, but if you trick Doom once, it won't happen again.
Happens with Reed because they are mortal enemies, they HAVE to get the better of one another.
Doom has shown his prowess in taking out beings of Loki nature before, I have no trouble seeing how he couldn't do so again, hasn't happened though so I can't say how he would deal with this particular person but given that he knows him and has encountered him before, I think he would get it.
-AC
Its true than Doom has absorbed the power of silver surfer and galactus before, but i think that loki is a bigger problem for him. Because loki is more than him, basically , he is doom with god powers. He is as smart. and vicious and with an ego as doom is. He would be more difficult for doom than galactus or surfer.
If you wanna be technical, Loki isn't a "god," he's the son of a Frost Giant, if that means anything.
For the record: Vicky's smarter than Loki, he is a lot faster (in flight speed and reflexes,) he's equally adept at using magic, he's far more knowledegeable in science, he's just as durable, and he's WAY better at fighting. Loki's just a little stronger.
No he isn't. Check out www.marvel.com. Compare their abilities. Doom is faster, and he's just as good at magic. He's smarter, and a better fighter too.