Ocks admantanium arms made him more powerful and he battered the Hulk with them when he was taken by surprise and Ock has beaten Spiderman (although he was ill).
But these wins were when he took them by surprise and they got overconfident.
The rematch with Hulk was about a page long Hulk grabbed his arms pulled him in and knocked him out with a flick of his finger.
DD should know about Docs upgrade and Ock would have a hard time hitting him and at the end of the day powering those arms is an overweight, Out of shape, Glassed jawed middle aged man.
One or two decent right hooks or kicks from DD lights out Ock.
Ock is better as a manipulator and leader than he is as a hand to hand combatant.