Medusa vs. Spider-man
divaI think Medusa will knock the bugs out of Spider-man. With her Super Strong hair she's more than a match for many of Marvels big guns.
She might not be able to move the Blob; but then who can.
Now I know she can't deflect small projectial like bullets, but even faceing the Hulk who throwing boulders she might toss him around too.