Original Lobo can't lose to WW. If the original Lobo gets caught in the lasso, the hundred clones would then murder WW. Not to mention she won't know who the original Lobo is.
I'm not even sure the Lasso would even work on Lobo seeing he's less of a being and more of a force of nature, he's even been called an "abstract being" before. Plus, mind control don't work on him.
Plus, with his weapons and bike, he's like the Silver Surfer, he can do thousands of times the speed of light on his bike and come at WW before she knows wtf has happened.
His own speed is superhuman as well, fast enough to surprise Superman. And he knows thousands of martial arts, plus he knows WW's weakness to pointy objects and he's got tons of those.
I just don't see how WW wins against Original "I beat skyfathers and lift the weight of the universe with one arm" Lobo.