Dont know much about BC except tat the name sucks 🙂
This scream thing is a important factor. If PP can quick web her mouth (or just speedblitz her for a little spider kiss^^) then he wins.
If her scream goes in all directions, is she then hit too? Or is she immune against her own scream?
Hey PP could make a device to protect his ears, i mean he is genius scintist. And since he lives in the Avengers Tower he could ask Tony Stark for some technical devices to fix something against her.