Dodging Dooms attacks won't be a problem for Spider-Man, in theory he can do that all day long.
The problem is, Doom has so many built-in weapons, it's inevitable that sooner or later SM will get hit. And he can't hurt/damage Doom either, or at least not much.
(However, I think that a well written, pissed off SM who uses his brains can hold his own for a good time against Doom.)
Originally posted by golem370
I said this about Spider-Man vs Colossus he could rap Doom in Webing and fling him like a mile way and keep doing that Dr Doom only weights 420 pounds Spider-Man lifts 10 tons he could easily toss him around. Tie Doom up and toss like he did that 3ton wrecking ball