Piedmon
Saiyajin Quaterback
Depends. Like someone else said, it took V YEARS to slowly set up everything in just the right way for his plan. Plus, he was up against a large and extremely centralized government. The Punisher is a lone man, a very different sort of opponent.
Also, while he is stated as superhuman, V lives in a much more realistic world than the Punisher. In Marvel 616, "peak human" is a very flexible term that encorporates a number of blatantly superhuman feats. In other words, if V were in Marvel Comics he'd probably be considered an ordinary but well-trained fighter, wheras in a realistic world with applicable physics he's above-human.
Now, I don't have the comic with me (it's been lost for about six months now, sadly), but I THINK they mention that V's intelligence was enhanced. Honestly, it comes down to a number of factors: is the fight in New York or London? Is it in Marvel-Earth, or V's alternate 1982? Why are they fighting, do they have any objectives beyond killing each other?
I suppose it's a none-answer, but it's the best I can do. Awesome match this would be.