??? Huh? Invisible woman alone could probably decimate the new F4. Not to mention the new F4 have no real leader or big brain....thats how they were so easily conned into being the new F4 to begin with. They werent so much a great or balanced team like the real F4 they were just really cool...realistically no match tho.
Err....too bad he cant. Wolverine uses his most deadly attacks on a regular basis which is cutting people. Imagine if Reed did the same thing, just like the Super Skrull, going around cutting an entire group of enemies like superhuman piano wire. Or how about Reed using his powers to entire Wolverines eyes, nose, and ears, scrambling his brains. Even if Wolvie can heal from it he'd still be out of commision for a good while.
Ghost Rider would be the only real threat...and even then he's not much of a threat, just really tough to "kill".