Flash,Runner & Makkari vs Ion with twist
Three uber powerful speedsters vs Ion
Flash- http://en.wikipedia.org/wiki/Flash_%28comics%29 & Power suit
Despite his growing insanity, Superboy-Prime exhibits the same Kryptonian super-intelligence shared by the pre-Crisis Earth-One and Earth-Two Supermen by designing his power suit. Patterned after the Anti-Monitor's armor, it collects and feeds him yellow solar energy. It is destroyed when the two Supermen fly Superboy-Prime through Krypton's red sun
The Runner- http://www.marvunapp.com/Appendix/runnerelder.htm & Reality Gem (yellow) - Control over reality itself, creating and uncreating matter and energy.
Owners: Collector, Thanos, Adam Warlock, Rune (Ultraverse), the Night Man (Ultraverse), Loki, Galactus, Darkseid (DC Comics)
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Makkari- http://www.marveldatabase.com/wiki/index.php/Makkari & Power Gem- Power Gem (red/pink*) - Increases physical strength and endurance.
Owners: Champion, Thanos, Adam Warlock, Drax the Destroyer, Magus, Thor, Rune (Ultraverse), Lord Pumpkin (Ultraverse), Loki, Galactus, Champion (again), Titania, Darkseid (DC Comics), Dr. Doom (in Mega Morphs, which may not be canon)