Sentry's light powers would only feed Hyperion.
We've seen Sentry bleed after taking shots from Ultron, though I'm rather suspicious of that comic.
Hyperion laughs at punches from the Hulk, injuring him is near impossible. Especially when you take into consideration his healing factor. Heat and energy based attacks have been proven to be useless against him.
Hyperion's problem would be his speed. I think it would be possible for Sentry to speedblitz him. IF telepathy works, then Sentry could probably take this one.
Physically beating Hyperion to death won't happen. He heals a snapped neck in two seconds.