sue can put a bubble in thor and expand it or
She can manipulate her bubbles anyway she likes (almost like a GL). She can create invisible battering rams with tremendous knockout force. She can create invisible cutting disks, spears, darts, that can cut through solid steel with ease. Thor won't be able to see these things coming at him (let alone her) to block them. And if she's invisible and flying around in her shield, then she won't suffer much damage to her shield because Thor won't know where she is or from where the invisible weapons she throws at him are coming.
With that said,
Thor definitely has some troubles on his hands.
Otherwise show how Thor escapes the bubble tactic let alone the flying around invisible throwing invisible things at him.