if i had to vote for someone it would probably be deadpool. seeing him in action with his blades against wolverine shows how much skill he actually has. in the first 30 issues or so of his comic he was almost unstoppable in melee combat. then he became too much of a joke character.
it wont be an easy fight for him, but the healing factor tips the odds too far in his favour. even when his body was turning into liquid he managed to beat sabertooth.
Alexander Anderson skewers Leo's punk ass and laughs while doing it.
Kinda like this....
http://img530.imageshack.us/my.php?image=hellsingv1c5277cx.jpg