Originally posted by X-43D
Superman's main weaknesses are kryptonite and magic but other strong forces like Darkseid's Omega effect can also hurt him.
The Omega Effect acts differently with Kryptonians. There is something in their physiology that makes them vulnerable to their technology. There is also the case in which a mother box can alter their abilities. So I think New Gods technology with Kryptonian powers could be more powerful than previously thought.