Originally posted by Faunus
Challenged, yes. But Anakin has no chance whatsoever of killing any of them, especially when the Force abilities of these individuals are taken into account. Mace is probably the only one there whose life would truly be at stake on any level, and even then Vaapad and shatterpoint give him a sharp advantage. The rest would Force (pun intended) Skywalker into the ground.
No chance whatsoever? Well, it depends on the combatant. He wouldn't have a chance in hell in defeating Bane in combat (his style is completely useless against Bane's orbalisks. Even physically, Bane holds the advantage), nor does he have a chance beating Yoda (smaller, faster, more agile, more percise. Anakin probably couldn't even land a strike on him), nor could he possibly defeat Luke (do I really need to post an argument?). Sidious is likely to be included in this category, too- Sidious is faster and holds an immense psychological advantage over Anakin. However, when it comes to Jacen... I don't know anymore. Does he really have feats that put him firmly above Anakin in saber combat?