ok hun, since i'm bored i'll engage in your observations. I realise Mephisto is not a genie, however is it to fantastic a thought that perhaps it is within his abilities to grant such a wish? I mean did he not just rewrite history on a universal scale in the "one more day" storyline? So i think it would be well within his power to "make" Rhino a genius. Everthing else is fathom-able. Disenfranchised villains with scores to settle all holding allegiance to a new big gun. Then in turn, plotting to take over Marvel Earth. Now i know the heroes would rise to the occasion, F4, X-Teams, Avengers new and mighty, T'challa and his kingdom, Thor and his pantheon. But the question is would they act quick enough? The only singular characters powerful enough is Sentry( who would not act), Thor, Hulk. But i see what you mean about the endless possibilities so i will lessen the meandering alternatives.
ARMY
Hellfire Club (including Emma)
Sinister Six
Current Thunderbolts
The Wrecking Crew
Opposition
X-Men ( Jean no phoenix force
All current Avengers
F4
Omega Flight b4 the got murked by the Collective
that should make it bout even i think