Kessler Vs. Wesker

I think Kessler has a higher chance of winning, if it was just a fist fight nothing else I'd be inclined to say Wesker but given the amount of power Kessler has and how much damage he takes and walks away....I really doubt Wesker could win.

Wesker has speed but so does Kessler, I imagine Kessler can create a sort of electro magnetic field so bullets are no real good, even then Kessler has a ridiculously large amount of health, and well could Wesker actually lay a punch on Kessler or does he have abilities to block any sort of incoming physical attack (at a speed?)

Kessler hasn't really suffered much physical damage. The most he has suffered was Cole overpowering him in the end, throwing him back and going all "DIIIEEEE!" lightning strike on him. Zeke shot at Kessler, but his bullets proved inefficient. It merely sparkled where they hit and Kessler didn't so little as flinch. But the lightning strike packs a pretty insane amount of physical force. It sends cars flying and busts trucks.