All Comic Characters at the same power level and speed level.

who is the best fighter in hand to hand

Too many characters dude. That's well over 8000 characters. How about you give a list. That's a start.

focus on the character who actually trained in some fighting art. eliminate the ones who rely solely or mostly on nonphysical combat, their superspeed, and superstrength, to win their battles. if i could make a list i would but i dont know where to start. Ra's al gul would be the best i could think of and im pretty sure somebody might be a better fighter than him

Doom
Kyle

Rhino.

Shit, forgot about Rhino.

Best martial artists would be Karate Kid and Judomaster.

KK