He may win with Galactus's eyeblasts though, assuming he has time to attack. Jurgen's HP DD (not Loeb's OWAW DD) was intended to be immune to be beyond all energy projection less than universal level.
Now in HP there were missiles made out of some indestructible adamantium like metal that was so durable that Superman with all his might couldn't even put a scratch on. Yet with a simple and single OE blast beam (OE usually hits with two beams) from miles away DS instantly vaporized the missiles (they became instant vapor). But HP DD took the same blast but with both beams instead and under point blank range with absolutely no shown damage. It is fair to suggest that not even Galactus eye beam would do anything.
Lastly, Spider-man is already almost as fast as quicksilver. And even with Quicksilver's speed he still may be a statue when DD decides to attack with his top speed (speed that Superman, the man who can pick bullets out of the air like they're standing still, complains about).
With all that said, Spider-man cannot win as he is not strong enough to hurt DD at all. If Galactus eye blast even bothers DD, then DD just evolves past it.
Originally posted by Enyalus
You gave Spiderman 7 different upgrades. It's not even Spiderman anymore.Why use him at all in that case? 😬
Because he still has his greatest power of them all, His SPIDER SENSE!!!
Also he keeps his grade A agility which plays a huge role in dodging attacks and attacking in a fluid and dynamic way.
Lastly Spidey's strength wasn't upgraded so this makes it more or less the real spidey.
Originally posted by DarkOdin
Maybe he uses Galactus eyes beam and amps them into mjolnirok thats 3
Yup Spiderman's screwed
Galactus' eyeblasts blew Rulk across time and space, sending his ass crashing back to Earth.
Spiderman wins all 10 via the eyeblasts. Doesn't even have to attempt killing DD. BFR suffices every time. BFR with Mjolnir, too, for that matter.