Sing vs. Agent Smith
Sing from Kung Fu Hustle versus Agent Smith from Matrix Revolutions.
Setting: Downtown Los Angeles with lots of buildings and shit.
Scenario, just for shits & grins: Agent Smith wants to impregnate Sing with a bug, like Neo in the first Matrix film, because he wants Sing to help him find Morpheus. Sing refuses and the fight begins.
Both are at full power.
To the death.