We've never seen X fight anybody using his own skills and talents....he always uses his powers to predict their movements.
The only instances of him not being able to use his powers was against Luke when his brain was scrambled...Iron Fist using Drunken Fist, and Luke and Danny hitting him at the same time.
If those are the only instances we have, they're all we have to go by. So if he can't read your mind, he gets beat, melee or not.