I like the reluctant vampire portrayals of recent films such as Thirst and Let the right one in (or "Let Me In" for that matter). They connect more than the more traditional view of vampires (to me anyway)
To me there only seems to be the 2 types of Zombie movie...The dead coming back to life or the virus infected type. Obviously the latter is the more "realistic" scenario. I think it's also been portrayed better in recent years with examples such as 28 days later and I am Legend. Along with genre crossovers such as Shaun of the Dead and Zombieland.
As for Werewolves...Hit and miss for me...Wolf man was not for me at all....Night Watch and Day Watch were...
As for Demons and the Devil...I know comic fans hate the mention of it but Constantine is a great examples...Peter Stromare is great as Satan. There have been other brilliant portrayals in different genres too though...Al Pacino in The Devil's Advocate...Even the tiny part that Rosalinda Celetano in Passion of the Christ was extremely effective and creepy.
As for other Devil and Demon portrayals...Linda Blair in The Exorcist obviously deserves a mention.
I still say Colm Feore as Andre Linoge (Legion) in Storm of the Century is one of the most intimidating bad guys in all of film...Even if the film itself is a cheap adaptation of Stephen King.