As much as I love Thanos he wouldn't stand much of a chance. Maybe one on one it would be different. Moondragon and Gamora could probably do it with just the two of them working together. Just use the mind gem to distract him while Gamora kills him with the Godslayer. If you wanna make it interesting since Moondragon gets to keep the mind gem let Thanos keep the Reality gem.
Originally posted by BrockalizerHe doesn't,and it broke on his skin when she tried to kill him with it during Thanos Imperative. And he also killed Gamora before when she tried to kill him with it years ago in a Marvel 2in1#2
If they couldn't do shit as you say, then why does Thanos fear Gamora's Godslayer?