Stryker wants a new Weapon
After Weapon XI is defeated by Wolverine, Stryker decides he wants to build Weapon XII.
He somehow captures Ultraviolet and Alice (Resident Evil.) After sedating them, he goes to work.
Into Ultraviolet, he injects the DNA of John Wraith and Carrie White (Carrie.)
Into Alice, he injects the DNA of Nightcrawler and the DNA of Charlie McGee (Firestarter.)
After Alice and Ultraviolet fully bond with the DNA injected into them, he decides to have them do battle to see who will be Weapon XII.
Ultraviolet retains her Hemophage powers, and inherits the combined powers of Wraith and Carrie. She is armed with her guns and swords.
Alice retains her powers, and inherits the combined powers of Nightcrawler and Charlie. She is armed with her guns and twin blades.
So who is Weapon XII? He will not be controlling them like he was XI, they will think and act for themselves.