Kid Icarus: Uprising
Cuz I ain't seen a thread for it yet in over the year since it's been announced, I may as well bring this out here. Though I took it with little more than a grain of salt at E3 2010, E3 2011's trailer and extra news really began to help it pique my interests. The production value seems pretty good (including fully-voiced cinematics, and pretty grand scale battles), and I especially liked the look of the weapons variety and the beat-em-up/shooter mixture to the gameplay.
Enough talk. Here's vids:
E3 2010 trailer
YouTube video
E3 2011 trailer (highlighting the multiplayer)
YouTube video
Discuss.