Took an RPG to the face no problem, got blasted point blank by Chamber, flew a couple miles and got up right after he landed. Takes slashes to the face by Wolverine and Sabretooth with no problem. His healing factor plus his natural durability and armor have him taking hits from people like Colossus with no issues at all. And as soon as the fight starts he'll be releasing his spores, which will weaken Aquaman a great deal anyway. So even at his full strength, he wouldn't be able to one shot him.