Ultron vs. Despero

Both at their best

Who wins?

If Despero is unable to warp adamantiun he loses to the point that it becomes a no contest.

Despero during Virtue and Vice was a beast but he used a lot of telepathy in that infamous fight.

Telepathy is useless against Ultron. With an Adamantium casing, the machine is far more durable, more versatile and possesses similar levels of power.

Going to go with the A.I.

Ultron.

Ultron in a no contest

Ultron's just a bad matchup for Despero, but it's still a hell of a fight

Ultron solidly.

Ultron after a tough fight

Ultron solidly.