The Punisher vs Hank Pym
The Punisher reads online one day that Avenger/evil robot creator/schizophrenic scientist Henry Pym may hit his wife once time over thirty years ago(No context for why this happened is provided). This enrages Frank to the point that he wants to show Henry what he thinks of wife beaters, and he gets out his arsenal of special toys just in case the superhero is foolish enough to not want to be properly punished.
Hank Pym is his laboratory, and is given a thirty second warning that Frank is coming for him before he arrives.