Agent 13 vs Crossbones

Bloodlust is ON
Fight takes place in a warehouse

Who would win if:
1) Both are armed to the teeth with assault rifles, machine pistols, pistols, grenades, etc
2) It eventually comes down to hand to hand

Bones in both.

Sharon is good and underrated, but she really can't hope to win here.

Agreed, Sharon only really has a chance at mid range as she isn't the shot Brock is and she can't deal with the physicality difference up close.