Technically not even the most powerful version of Thor or Ironman should be able to even tickle hyperion. But after the little thanos saga, if you have and Thor that remember how to fight, and Ironman that hitting hulk with enough power to power a continent, they an win. Thor can easily generate power to decimate planets, Ironman could easily mess up Hyperion senses enough to throw him off. They could do it but Some bodies probably gotta die every fight.