1. Spidey is physically superior across the board. But Cap gets his c*ck sucked by Marvel all the time and does ridiculous stuff. In a forum fight, Spidey should take a majority.
2. Spite against Cap. Spidey was casually catching police cruisers and stopped a bus being pushed by an 18 wheeler. Also he was dodging electricity and bullets at point blank range. A single hit and Cap is done.
3. Even more spite against Cap. Spidey in the comics is like exponentially more powerful than the movie...and that's him holding back. Another one shot.
4. Spidey puts up a good fight, but Comic Captain probably takes it.