The twins were the darth maul of this movie and I hate that.
Spoiler:
I do think they will because in the scene when they are invovled in the explosion it looked like they "ghost'd" out to avoid the blast. keep in mind that only my opinion, but I hope they do. They weren't in the trailer for revolutions though.
I think they will be in the next movie, they appear to be another program outside of the Matrix and therefore they are against the Agents, they will only go against Neo again if he is going to affect the power that Merovingian has, can't see them bothering him too much because the Key Maker is dead/deleted.