Yeah, it would be impossible. But if he will be able to subdue Plo with his own powers, while fighting Galen in lightsaber duel (the way he was fighting Anakin and Obi-Wan in ROTS), he might be able to overhelm Marek and, let's say, kick him away. Then he will has a few seconds to deal with Plo, which might be enough. But in the other way, he wont be able to defends himself against Marek's Force powers and Plo's blade or Force powers as well at the same time.