Can Dooku defeat these guys

Dooku vs Plo Koon, luminara Unduli, Quin Lin Vos, and Aayla secura

Hmmm location?

Yes, he can.

It's possible, but unlikely.

He'd probably lose, is what I'm saying.

No

If he's amped by a stone prison that cancels out the drugs, probably

Location is where he fought yoda

I'd say dooku can, but he would have to bring on his A game as its like 5 of them. He could take out Quinn Lin and undulli easily but he has to be careful for plo.

Probably not

He can definitely do it, doubt it'd be for a majority though.

Yeah if he uses telekinesis probably. Plo is skilled enough to pose a challenge, but he'd get overrun eventually