Marvel has 2 of the longest female runs of all time. Patsy Walker and Milly the Model. Wonder Woman comes in 2nd and 1st.
http://www.newsarama.com/15464-the-10-longest-running-solo-female-comic-book-series.html
It's not just woman in comic books, but it's ALL comic books characters. It's becoming more rare for a series to go past issue 10-12. In Marvel if they don't have the X-Men, Avengers, etc in their name most fail. Even Hulk has been retooled and rebooted what? 3-4 times in the past few years same for Fantastic Four.