Originally posted by AuraAngel
No one in this fight is killing Daz Bones since he could take a slash from Mihawk(only 1 but he was also "weaker" apparently). The only way Oto is stopping his is through Genjutsu or Sakon/Ukon/Orochimaru invading his body. The others are less of a problem but Bon Clay should be physically above any of the Sound Five sans Kimmimaro. They'll probably take Round 1, depending on how well the Sound 5 focus their efforts.
On the flip side, the agents aren't well suited to genjutsu, and Ukon merging is a threat.
For pure physical stats, note how strong Jirobo is, and that's from his non-cursed seal form. In his seal form, he was throwing around giant Choji.
And sure, Daz Bones and Bon Clay are strong, but Mr. 4 *just* has strength, and even with his partner (Btw, are the partners included?) has nothing on Jirobo, let alone the others.
Mr. 5 has some offense, but defensively he's pretty weak, and he's very straightforward.
Mr. 3 has creativity, but even he doesn't have the range of abilities of a lot of them.
And don't forget the Four have options like Tayuya summoning giants (frankly the giants on their own could beat the lesser agents), Jirobo trapping the lesser foes in a dome, Sakon and Ukon summoning a metal gate to slip the battlefield in half, and such.
Baroque Works increases power with rank, while most of the Sound Four are basically on the same fairly high level. So the top Baroque agents are trouble for them, but the lower officer agents are in major trouble.