Most of the time, realistic power set advantages don't matter that much in comics. Character's tend to perform based on their overall, raw power ranking. Writers find a way for higher power characters to beat less powerful characters, even if they shouldn't. There's always a manhole cover for the Hulk to frisbee into the ranged-attack flyer who is trying to kite him lol
So I don't typically subscribe to the Rock-Paper-Scissors theory. However, sometimes one character is so setup to beat the other that it's hard to see the writer ignoring it. The outs for the more powerful brick would just be too contrived, even for comics. Monica might be like that vs. a pure brick like say Hercules.
I could possibly see Gladiator injuring Monica with his vision attack, somehow, though.