Yeah, I went back and re-watched the Nuke/Jones fight. He does admit that she would take him uninjured, but he still did a real number on her when she was. I'd forgotten that he actually tossed her right through a wall at one point. I still feel that Frank is more skilled though, even though Simpson is hardly unskilled in H2H. And both can be extremely ruthless when necessary. But yeah, after reviewing his feats, I think Nuke takes it too. Not only is he extra strong, he is also extra tough, and has enhanced recovery time. With the aid of those drugs, he survived and recovered within a day or so from a large explosion which instantly killed the rest of his crew IIRC.