Originally posted by Scribble
There are members here who have been reported for shitty behaviour countless times and never been banned, but lord above you criticise the mods. Especially if you hold certain points of view. The modding here is highly selective.
It is their prerogative. Do not like it? Do not post here. If you choose to continue to do so anyway, then you have accepted it, and should remain silent. Either way, no one is interested in your bitching about it.
Originally posted by QuincyQuite possibly, and quite possibly very regularly. It depends how lethal the levelled off Coronavirus mutations tend to be... perhaps. We still don't really know, it's possible the standard yearly variants will turn out like the flu... It's possible they will turn out much worse, which is why we need to be able to produce vaccine variants...
We all gonna get sick
Originally posted by Old Man Whirly!
Quite possibly, and quite possibly very regularly. It depends how lethal the levelled off Coronavirus mutations tend to be... perhaps. We still don't really know, it's possible the standard yearly variants will turn out like the flu... It's possible they will turn out much worse, which is why we need to be able to produce vaccine variants...
Since this is an mRNA vaccine, it should be effective against the mutations as well. It does not teach your body to recognize a particular strain of the virus, it teaches it to recognize the spike protein that all variations of the virus should have.
Originally posted by Adam_PoEIt should, but no one is one hundred percent certain yet. Hence the further testing going on, the biggest problem is the rat of mutation and the way the mutation works.
Since this is an mRNA vaccine, it should be effective against the mutations as well. It does not teach your body to recognize a particular strain of the virus, it teaches it to recognize the spike protein that all variations of the virus should have.
Moderna did not immediately respond to a request for comment but said in a statement provided to other media outlets that it expects “that the Moderna vaccine-induced immunity would be protective against the variants recently described in the U.K.,” and that it “will be performing additional tests in the coming weeks to confirm this expectation.”
Pfizer pointed out that when SARS-CoV-2, the virus that causes COVID-19, first emerged a year ago, it was clear there was more than one strain of it, and that it was mutating as it spread. SARS-CoV-2 is an RNA virus, and as such, it has “exceptionally high [mutation] rates” because the enzymes it uses for replication are “prone to errors when making new virus copies,” the company said.
“One of the reasons Pfizer and BioNTech chose to utilize a mRNA platform is because of the potential for the flexibility of the technology in comparison to traditional vaccine technologies,” including the ability to change the RNA sequence in the vaccine, should a strain emerge that’s not covered by the current shot,” Pfizer added.
Truth is, its all still guess work, computer modelled guesswork i'll grant you, but guess work none-the-less Adam.
Originally posted by -Pr-
Dude wtf is up with your sig...
🙂 Do you like it?
Originally posted by Old Man Whirly!
It should, but no one is one hundred percent certain yet. Hence the further testing going on, the biggest problem is the rat of mutation and the way the mutation works.Moderna did not immediately respond to a request for comment but said in a statement provided to other media outlets that it expects “that the Moderna vaccine-induced immunity would be protective against the variants recently described in the U.K.,” and that it “will be performing additional tests in the coming weeks to confirm this expectation.”
Pfizer pointed out that when SARS-CoV-2, the virus that causes COVID-19, first emerged a year ago, it was clear there was more than one strain of it, and that it was mutating as it spread. SARS-CoV-2 is an RNA virus, and as such, it has “exceptionally high [mutation] rates” [b]because the enzymes it uses for replication are “prone to errors when making new virus copies,” the company said.
“One of the reasons Pfizer and BioNTech chose to utilize a mRNA platform is because of the potential for the flexibility of the technology in comparison to traditional vaccine technologies,” including the ability to change the RNA sequence in the vaccine, should a strain emerge that’s not covered by the current shot,” Pfizer added.
Truth is, its all still guess work, computer modelled guesswork i'll grant you, but guess work none-the-less Adam. [/B]
It is not exactly guess work. The science that was used to produce an effective vaccine is the same science that predicts it will work on variant strains. If they model that predicted it would work is correct, then the same model that predicts it will continue to be efficacious should also be correct. It is not blind guessing, it is reliabile inference from proven successes.
Originally posted by Adam_PoEYeah, it's computer modelled, but it's reliant on mutations of specified sequences not happening, I'll grant you that. What we know from 3.5 billion years of mutation is we don't really know and can't predict much with certainty. Especially when the virus is only made of around 1300 amino acids land it only takes about 10 changed to mutate it in the ways it has been in the present variants, we don't know how many mutants are out there our how fast it mutates. In about 100 mutations this vaccine probably won't work, how fast it gets to that and if changing the vaccine payload in response will cause side effects is also unknown. Tertiary structures can be a *****. -edited for clarity.
It is not exactly guess work. The science that was used to produce an effective vaccine is the same science that predicts it will work on variant strains. If they model that predicted it would work is correct, then the same model that predicts it will continue to be efficacious should also be correct. It is not blind guessing, it is reliabile inference from proven successes.
Originally posted by Old Man Whirly!further clarification 100 distinct mutations
Yeah, it's computer modelled, but it's reliant on mutations of specified sequences not happening, I'll grant you that. What we know from 3.5 billion years of mutation is we don't really know and can't predict much with certainty. Especially when the virus is only made of around 1300 amino acids land it only takes about 10 changed to mutate it in the ways it has been in the present variants, we don't know how many mutants are out there our how fast it mutates. In about 100 mutations this vaccine probably won't work, how fast it gets to that and if changing the vaccine payload in response will cause side effects is also unknown. Tertiary structures can be a *****. -edited for clarity.
Originally posted by Old Man Whirly!
https://www.azfamily.com/news/new-billboard-in-downtown-phoenix-shows-president-trump-in-prison-jumpsuit-behind-bars/article_6faf4aa4-40ce-11eb-81ef-9ffd8360fce1.html🙂 Do you like it?
Link didn't work for me.
Far as my opinion goes... eh.
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On topic though, fingers crossed i get my vaccine soon.
Originally posted by -Pr-Absolutely, as soon as we get it in Nigeria, I will be paying for the Mrs and I to have it straight away.
Link didn't work for me.Far as my opinion goes... eh.
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On topic though, fingers crossed i get my vaccine soon.
Basically this!
PHOENIX (3TV/CBS 5) - There's a new billboard in downtown that shows where anti-Trumpers hope President Donald Trump ends up after leaving the White House.
The billboard features Trump in an orange prison jumpsuit with behind bars. He has a name tag that reads, "Don the Con." There are also mushroom clouds behind him with swastika-like dollar signs next to him. The billboard is on Grand Avenue near 11th Avenue.
Controversial Trump billboard still looming over Grand Avenue after a year
Controversial Trump billboard still looming over Grand Avenue after a year
If you spend any time on Grand Avenue in downtown Phoenix, or anywhere nearby, you’ve seen the controversial billboard of President Trump for 365 days.
Just below the picture of Trump is a digital crawl that says "TRUMP DEATH CLOCK" and then gives the number of COVID-19 deaths in the U.S., which is more than 311,000 as of Thursday night. It also says people should wear a mask
Originally posted by BrolyBlackFunny that, the entire second post is mine.
If you stopped copying and pasting stuff and had a genuine discussion you might get somewhere
Originally posted by Old Man Whirly!
Yeah, it's computer modelled, but it's reliant on mutations of specified sequences not happening, I'll grant you that. What we know from 3.5 billion years of mutation is we don't really know and can't predict much with certainty. Especially when the virus is only made of around 1300 amino acids land it only takes about 10 changed to mutate it in the ways it has been in the present variants, we don't know how many mutants are out there our how fast it mutates. In about 100 mutations this vaccine probably won't work, how fast it gets to that and if changing the vaccine payload in response will cause side effects is also unknown. Tertiary structures can be a *****. -edited for clarity.
i was speaking of this post
Originally posted by Old Man Whirly!
Absolutely, as soon as we get it in Nigeria, I will be paying for the Mrs and I to have it straight away.Basically this!
PHOENIX (3TV/CBS 5) - There's a new billboard in downtown that shows where anti-Trumpers hope President Donald Trump ends up after leaving the White House.
The billboard features Trump in an orange prison jumpsuit with behind bars. He has a name tag that reads, "Don the Con." There are also mushroom clouds behind him with swastika-like dollar signs next to him. The billboard is on Grand Avenue near 11th Avenue.
Controversial Trump billboard still looming over Grand Avenue after a year
Controversial Trump billboard still looming over Grand Avenue after a year
If you spend any time on Grand Avenue in downtown Phoenix, or anywhere nearby, you’ve seen the controversial billboard of President Trump for 365 days.Just below the picture of Trump is a digital crawl that says "TRUMP DEATH CLOCK" and then gives the number of COVID-19 deaths in the U.S., which is more than 311,000 as of Thursday night. It also says people should wear a mask