Assuming someone could stop a Superman speedblitz, this is a fairly easy win for the Illuminati. Strange and Xavier alone present problems that none of those three have easy answer for. Obviously the Illuminati wouldn't want to brawl, but Batman is a non-factor without prep and BB could at least occupy Big Blue for long enough for the odds to become overwhelming.
Better thread would be Avengers Prime vs. Trinity.
Illuminati stomp. "Classic" Illuminati Strange was Sorcerer Supreme and was powered by the Vishanti, Bolt wasn't weakened by Maximus' bomb, Tony had his famous Extremis armor, Namor had his black suit... Xavier was pre-upgrade, but even pre-upgrade Charles was among the most powerful telepaths on the planet. Reed is a non-factor unless he has his toys.