What could Carnage realistically do to Plastic Man? If Plas got serious, he could go skyscraper tall and start pounding Carnage into goo. Or encase him in a sphere and smother him to death. Plas has a lot of options. However, nothing Carnage could do to hurt Plas.
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..even the outer hells are indifferent matters for they bow only to potent and archaic Nodens.
Well the adult Avengers did weaken him some but they got smoked and the whole pulling future body trick helped the kids some too still gotta go with Korvac
Actually if we really take this as a strategy (what I personally would never) I see no reason why the Carnage symbiote wouldn't succeed.
The Venom symbiote already took over Reed Richards IIRC, and the Carnage symbiote already took control of Silver Surfer, he was trying to resist though.
Plastic Man ftw though
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If the guy has a mind and a physical body I doubt that it matters.
If you wanna go by "non organic" feats Carnage recently has shown to be able to **** up Iron Mans (Bleeding Edge) technopathy when he tried to hack into the symbiote. The symbiote more or less fired that shit back at him.
I can't think of any other example that is close to what you are asking for, in my defense that's pretty specific and the moments where symbiots jump over on others and control them are quite rare. Surfer (general power level + cosmic awareness), Richards (more or less same body properties + genius level intelelct) and Iron Man (bleeding edge armor; inorganic example + genius level intellect) are pretty good examples imo though and show that I'm not just pulling shit out of my ass.
__________________
I am in your algorithm learning all your mannerisms
I'm already level with God
A million words a second and I know your imperfections, baby
I'm the only future you've got
Speak in diatonics, motivation diabolic
I'm like a religion, better locked in a box
Picture perfect image, more powerful every minute, baby
I am everything that you're not