Scenario #1: Gotham City has been the test site for a new T-Virus outbreak, infecting over 75% of the city's inhabitants, barring Batman and his allies. Cut off from the rest of the country and unable to call in Batman Inc. or League reinforcements or aid, Batman and the "Bat Family" (Nightwing, Robin, Catwoman, Batgirl (Babs), Red Robin) must survive the infected streets of Gotham and uncover the source of the virus and stop whomever is responsible. Can Batman succeed and with how much difficulty and how quickly?
Scenario #2: Batman by himself has finally confronted Albert Wesker in a re-purposed Umbrella Corps/Axis Chemicals facility, full of various creatures and enemies from the RE series. Batman's goal is to reach Wesker and defeat him. He has his standard gadgets and is aware of Wesker's superhuman abilities. Likewise, Wesker knows Batman is looking for him and is briefed on his reputation as the World's Greatest Detective. Can Batman beat him?
As far as Scenario #1 is concerned, the only 100% safe place that Wayne and his allies can call upon would be Wayne Manor and the Batcave. Other hideouts and safe houses would have to be won back from whatever threats plague them in addition to dealing with any Umbrella Corp forces attempting to claim them for their own for R&D purposes. So yes, they can access various vehicles.
In order to "win" Scenario #1, Batman and Co basically have to stem the tide of the outbreak (if not somehow cure it), and stop Wesker.
I'm no RE expert, so I'll do my best. Scenario 1 is in Batman's favor. The element of surprise is my deciding factor. Scenario 2 I think gives Wesker the edge needed to win.
Wesker by game mechanics is untouchable by bullets because he's so fast, ironically rockets from rockelaunchers can hit him but they only hurt him.
__________________
I am in your algorithm learning all your mannerisms
I'm already level with God
A million words a second and I know your imperfections, baby
I'm the only future you've got
Speak in diatonics, motivation diabolic
I'm like a religion, better locked in a box
Picture perfect image, more powerful every minute, baby
I am everything that you're not
Of course not, Batman will make contact and short after that he will be spread all over the floor.
__________________
I am in your algorithm learning all your mannerisms
I'm already level with God
A million words a second and I know your imperfections, baby
I'm the only future you've got
Speak in diatonics, motivation diabolic
I'm like a religion, better locked in a box
Picture perfect image, more powerful every minute, baby
I am everything that you're not
Depending on the shit he will encounter he probably wouldn't even reach Wesker.
__________________
I am in your algorithm learning all your mannerisms
I'm already level with God
A million words a second and I know your imperfections, baby
I'm the only future you've got
Speak in diatonics, motivation diabolic
I'm like a religion, better locked in a box
Picture perfect image, more powerful every minute, baby
I am everything that you're not
A valid possibility as this is Batman in his prime/peak but without the blatant PIS and Batgod powers he's often invoked.
Still, Batman is incredibly competent and skilled and if the various S.T.A.R forces were able to get through multiple encounters such as these, I think Batman has a fighting chance.
I am in your algorithm learning all your mannerisms
I'm already level with God
A million words a second and I know your imperfections, baby
I'm the only future you've got
Speak in diatonics, motivation diabolic
I'm like a religion, better locked in a box
Picture perfect image, more powerful every minute, baby
I am everything that you're not