Tough to say. It's factually true that the Separatist defeat was "preordained," as one source I know of puts it.
The Republic certainly triumphed more on screen and on page. But for what it's worth, the tactical droid Kalani in Rebels says a strategic analysis still favored the CIS at the end of the war.
Republic easily; they have Jedi and it is said that the Clones are immensely superior to Droids so yeah; the CIS may have the sheer numbers but the Republic Army had better skills and more power