kiekan
Studly Pic-Postinest
Now, for actually wearing one, that’s a whole different thing. I think you'd feel extremely healthy, seeing as the Symbiote’s can heal the host from just about injury and even make the host live normally when they have a fatal disease like Cancer (shown in Amazing Spider-man #430-431 with Cosmic Carnage, tells that Kasady has Cancer and that the only reason he is still alive is because of the Symbiote.)
Also, I think that when it’s in the form of casual clothing, it would just feel like an extra comfortable version of those clothes. This is talked about in Web Of Spider-man #1, where Parker talks about how comfortable he thought the Symbiote was when he wore it. I think that you'd feel as though someone were always watching you and always seemed to know what you were thinking (that is, if it makes itself aware to the wearer, like Eddie Brock or Ann Weying. It never did this when bonded with Parker or Reilly). When it spoke, I think it you would either see it as images in your mind or it would have kinda a dark, mysterious sounding, almost snake-like voice (that would be telepathic of course).
While in an actual Venom-type form, where the Symbiote covers the host's body completely, I believe it would feel like a second skin almost. Or like tape stuck to your skin that you couldn't take off. And if you tried, it'd feel as though you were ripping skin out (Shown in the end of the Maximum Carnage story, when Venom starts ripping the Symbiote off Kasady and again when he does it to Donna in Spider-man #52).
Also when the Symbiote takes control, I don’t think the host would even realize it. It'd be like he/she was doing the actions themselves.
Something to Note: None of my beliefs follow the recent versions of Venom. I really didn't like that whole arc in the begging of Spectacular Spider-man Vol. 2, where it made Brock look like a complete wuss and basically changed the Symbiote into a pathetic parasite with nothing better to do than go around and munch on adrenaline (that, in itself, was a stupid idea IMO).