The Black Cat is the obvious one and I think that'd add more of a twist to the relationship being that he knows his girlfriend is a superheroine. Felicia doesn't know Peter is Spider-Man, Peter doesn't know she's The Black Cat. At the same time, Spidey and Cat have to hold off attraction because they view it as cheating being that they're already in relationships, little do they know it's with each other.
It's better with MJ though because she's just an innocent bystander who's always there for him, yet gets dragged into stuff.
Sue Storm-Richards would never date him coz she's married. If Spidey ever tried anything Torch would incinerate him.
-AC
DEFINATELY, cus she'd have the same guilt feelings running all over her if she didn't help someone in danger when she could have. Then she might have a bit of understanding for her husband and hide it for a while and appear as an extra on astonishing spiderman as a new feminine superhero. That'd make a hit story as Peter would be so so shocked to find out his wife had been bitten by the mutant bug! Then he'd even be more paranoid as to try and defend her from super powered villians!
If Dr Ock was to find out , that make a great battle! I hope Marvel writers are reading this! Mary Jane the new Kat
I hope they give her some powers so she can share something secret with Peter and that could bind them closer together! You know, the with greater powers come greater resps thing!
Then the plot would thicken more as Spidey has to worry about her now1 They can share a laugh at their secret exploits and like Richard Reed and Invincible girl, Sue Richards, they can form a duo superhero thang! What you say homies?