"Well, I think one diffrence is the fact that Machines are created with with a purpose- so they live their existence more focused on this, perhaps it makes them more "practical' in some regards, focusing on efficient existence, and don`t letting themselves be as distracted from their purpose as it often happens with humans that think that they have " purpose."
And I think Machines are free from the many fears and anxieties that humans have to deal with. They are not going to die from old age, don`t have to be afraid of getting old themselves, I also assume that diseases are not a concern as well. I also doubt whether there is any equivalent of social insecurity or threat of violence in Machine Society.
So while posessing a fixed purpose, Machines may not have many motivations of humans- they don`t have to deal with constant rivalry, because they are not going to be replaced even if they do their jobs relatively poorly, and they don`t need to care about securing the future for their children as most humans do. So I suppose that Machines are less emotional than humans, and more likely to follow reason and logic instead of their basic fears and desires. Being effectively immortal, their ability to learn and acumulate knowledge may be unlimited, so they have potential to become very enlightened beings, having diffrent perspective than humans. On the other side, I am not sure if they do not become too stagnant after a long existance, not having any outside reasons to evolve or change their beliefs."