Dreampanther
We all face the reaper.
Has to be per genre, not overall - there are too many different elements to try and fit into one film.
For me, the list would be sorta like:
Scifi:
The Matrix
Inspiring drama:
Dead Poets' Society
Shakespeare:
Midsummer Night's Dream
Romantic comedy:
Roseanna's Grave
Comedy:
Groundhog Day
Marvel superhero:
Iron Man
DC superhero:
Batman Begins
Classic DC superhero:
Superman
Action comedy:
The Last Boy Scout
Psychological thriller:
Silence of the Lambs
Dark action:
The Crow
Documentary:
Amandla
etc...
I can pick a Best Of per genre, but overall? There are just too many elements to take into consideration, and no film that I can think of contains everything, from humour, to action, to beautiful scenery, to great acting, to great soundtrack, to an important message, plus special effects, etc...