I suspect the universe is probably teeming with life, that even our solar system has life "hidden" in extreme, off-Earth biospheres we have yet to penetrate. But like the ocean, you just can't walk up to the shore, scope out a glass of seawater, look, see nothing, then conclude the rest of the ocean is lifeless. The universe is simply too vast for that. But this sort of life is likely primitive or microbial.
Life with intelligence (*cynicism on hold here*) like us, or greater?
If Earth is in any way typical, I'd say such life is extremely rare, if for no other reason than, as we've seen on Earth, higher intelligence isn't exactly necessary for life to thrive.
My version of the Drake equation:
1. Since life began on Earth, I'd read that some 50 billion different species have come and gone (mostly gone).
2. Out of that 50 billion, only one -- 1 -- has risen to extreme technological eminence. So we now have a ratio of pre-intelligent life to intelligent life: 50 billion to 1.
3. The Milky Way is estimated to have about 500 billion stars. If we apply the same ratio on Earth to the whole galaxy, we have 10 stars with at least one planet harboring intelligent life.
4. With a galaxy 100,000 lightyears across, that puts the average distance between intelligent life systems at 10,000 lightyears.
5. 10K LY is far more than enough to keep any radio/EM-broadcasting (or certainly less advanced) civilization seemingly isolated and apparently alone.
6. Those at a "Star Trek" phase of exploration: aliens at that exact level of development, as we imagine (and what are the odds of that), could be out there, or not; could be close by, or not. (Regarding UFOs: I find no compelling evidence that these are alien visitations. If anything, given the *prevalence* of humanoid types, at worst that's a cultural trope; at best, if real, I would sooner go with time travelers from a far future.) In any event, given the distances and energy requirements, I would think interstellar flight via starships would not be as routine as our pop scifi generally portrays.
7. Those that are far more advanced than us (ie, using some other form of communication/transportation) likely aren't detectable by us, and they know better than to interact with a race at our stage of, um, development.)
Conclusion: Yes, I think there is intelligent alien life out there, but it is rare, again if only because intelligence isn't necessary for life to thrive (and indeed, if we end up destroying ourselves, than higher intelligence may be, in the longer term, actually counterproductive to extreme, long-term species survival).
/speculative lecture