Adult Naruto vs Adult Sasuke
Naruto can't use any of Kurama's chakra that isn't inherently mixed with his own. In other words, no chakra modes or biju forms. Kurama is, however, allowed to gather Senjutsu chakra for him like usual.
Sasuke can't use any of his Mangekyou Sharingan techniques, nor can he use his upper-class Rinnegan powers. (In other words, he can only use powers available to him when his Rinnegan isn't active with tomoe)
Who wins?