Originally posted by Gehenna
DDM:I had left a couple of these behind so I'll address them now.
Concerning this particular claim?
https://coronavirus.jhu.edu/testing/individual-states
^ The source above points to an initial deep dip and then? Since mid to late June, a steady upwards increase in positive cases per test.
https://coronavirus.jhu.edu/testing/tracker/overview
This source contains each individual state and some are increasing, some are decreasing. In aggregate, this seemingly manifests as growth in positives cases per test.
There's nothing we can discuss that has not already been discussed, in my opinion, because the data speaks for itself. Any thing we'd state would just be restating what is in the data and the graphs already exist for that - so we could just use those. We state anything contradictory to the data, we'd just be wrong. This is why I say let the data speak for itself.
Biggest thing that sticks out to me is there are now 11 states with increased deaths, 2 of which have not seen spikes greater than prior numbers.
July-16:
My original screen shots from June 28:
https://graphics.reuters.com/HEALTH-CORONAVIRUS/USA-TRENDS/dgkvlgkrkpb/
Originally posted by Gehenna
If you take a peek at the second link right above, it seems there are quite a few more than just four states who've seen positive cases per test go up.
If you take a look at the screenshots in time, when they were taken, it was just 4 states who saw deaths increase which is the reference to 4 states. I did not misrepresent the data.
Originally posted by Gehenna
Moving on, what I am about to address I did address partially earlier, and specifically highlighted how a collection of epidemiological studies supported the usage of mask due to rates of infectivity pre-and-post masking wearing (then stated the WHO and the CDC supported it and asked if you thought they were bullshitting), but would like to add further comment specifically concerning RCTs.Now, there are some RCTs but they're not quite the perfect sort of RCT that we would really desire (I'm not sure if such an RCT would pass an IRB). I go off of the summary of proof within this particular piece: https://web.archive.org/web/20200619074339/https://slatestarcodex.com/2020/03/23/face-masks-much-more-than-you-wanted-to-know/
It seemingly indicates that there is higher quality evidence in favor of mask-wearing than against. For example, it's likely good to don masks within indoor locations that are crowded where you'll be there for an extended period of time. That being said, no one reasonable thinks masks are a cure all. However, they're useful in mitigating within high-risk circumstances/situations.
Concerning HCQ/CQ, I don't think we have an RCT for those either, no? With respect to COVID-19, specifically.
In this next section, I've addressed all of this already. Including the content that you linked from the Web Archive (why did that site take down that article?).
I've even gone through 2 different meta-analyses which covered almost only quality RCTs (and they have a few study overlaps).
http://www.killermovies.com/forums/showthread.php?s=&postid=17229240#post17229240
http://www.killermovies.com/forums/showthread.php?s=&postid=17229241#post17229241
And this was my conclusion from all of it:
...respirators (N95s) worn continuously during healthcare shifts may, not guarantee, offer some protection against COVID-19.
Because some quality research found that even the N95s did not offer additional protection.
And all of this specifically applies to HCWs.
What happened with the RCTs on households, they found no benefit because people simply interact with each other too much and the virus gets everywhere:
Influenza transmission was not reduced by interventions to promote hand washing and face mask use. This may be attributable to transmission that occurred before the intervention, poor facemask compliance, little difference in hand-washing frequency between study groups, and shared sleeping arrangements. A prospective study design and a careful analysis of sociocultural factors could improve future NPI studies.
And to your last point, yes, we don't have any quality RCTs for COVID-19 for the general public because there's no way to control who wears and who does not wear a mask - the best you can do is a retrospective study and it cannot be an RCT or even highly quality due to the self-reporting nature.
You could potentially do an RCT based on people who guarantee they will not wear masks and still follow up with with verifications of masks (like in the Thai study) and only use lab-positive results (because multiple studies found that mask wearing creates a placebo effect and measuring that against lab results showed no benefit).