| POS | LW | MOVIE TITLE | WEEKS | WEEKEND | GROSS |
| 1 | 1 | Beverly Hills Chihuahua | 2 | $17,502,077 | $52,532,310 |
| 2 | - | Quarantine | 1 | $14,211,321 | $14,211,321 |
| 3 | - | Body of Lies | 1 | $12,884,416 | $12,884,416 |
| 4 | 2 | Eagle Eye | 3 | $10,913,762 | $70,409,979 |
| 5 | 3 | Nick and Norah's Infinite Playlist | 2 | $6,420,474 | $20,730,708 |
| 6 | - | The Express | 1 | $4,562,675 | $4,562,675 |
| 7 | 4 | Nights in Rodanthe | 3 | $4,541,201 | $32,297,101 |
| 8 | 5 | Appaloosa | 4 | $3,321,389 | $10,867,693 |
| 9 | 20 | The Duchess | 4 | $3,304,841 | $5,603,061 |
| 10 | 8 | Fireproof | 3 | $3,140,997 | $16,875,765 |
| 11 | - | City of Ember | 1 | $3,129,473 | $3,129,473 |
| 12 | 6 | Lakeview Terrace | 4 | $2,654,644 | $36,201,729 |
| 13 | 10 | Religulous | 2 | $2,230,898 | $6,732,631 |
| 14 | 7 | Burn After Reading | 5 | $2,095,647 | $55,177,399 |
| 15 | 9 | An American Carol | 2 | $1,395,000 | $5,971,000 |
| 16 | 11 | Flash of Genius | 2 | $867,780 | $3,744,790 |
| 17 | 16 | Tyler Perry's The Family That Prey's | 5 | $840,767 | $36,405,889 |
| 18 | 13 | Igor | 4 | $560,410 | $18,073,854 |
| 19 | 21 | The Dark Knight | 13 | $528,328 | $526,690,914 |
| 20 | 18 | Ghost Town | 4 | $502,402 | $12,500,221 |
| 21 | 12 | Blindness | 2 | $486,726 | $3,073,392 |
| 22 | 15 | Righteous Kill | 5 | $483,131 | $38,804,543 |
| 23 | 17 | My Best Friend's Girl | 4 | $480,233 | $18,748,603 |
| 24 | 14 | Miracle at St. Anna | 3 | $480,116 | $7,441,895 |
| 25 | 27 | RACHEL GETTING MARRIED | 2 | $445,628 | $863,746 |
| 26 | 19 | How to Lose Friends & Alienate People | 2 | $440,066 | $2,458,092 |
| 27 | 29 | Wall-E | 16 | $409,355 | $221,595,782 |
| 28 | 31 | Journey to the Center of the Earth | 14 | $293,885 | $100,455,415 |
| 29 | 24 | Vicky Cristina Barcelona | 9 | $252,468 | $21,445,663 |
| 30 | 22 | The Women | 5 | $225,534 | $26,484,661 |
